from Washington: The Indispensable Man by James Thomas Flexner:
No one then understood how yellow fever was transmitted. Unsuspected by science, mosquitoes took over Philadelphia. In August, 1793, the disease moved on insect wings down the streets from the waterfront, creating the most murderous epidemic in all American history. Hamilton was soon believed to be dying. Those still-living inhabitants who had not fled the city, cowered indoors, the principal movement on the streets being of open carts driven by blacks (Negroes were considered immune) on which sprawled corpses being hurried to the pits which had taken over from the glutted graveyards.
The presidential office, Washington wrote, was “in a manner blockaded by the disorder,” yet word came to him that his presence in the city was one of the few things that gave inhabitants hope. Although he had announced a date for his departure for a Mount Vernon holiday, he decided to remain. However, Martha could not be persuaded to leave without him. Unwilling to expose her and the children to the contagion, he agreed to leave, but not one day sooner than he had previously intended.

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